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    Home > Related Disease > Polycystic Kidney Disease > Polycystic Kidney Disease Basics >

    Polycystic Kidney Disease: Basics and Causes

    2014-03-10 16:04| Font Size A A A

    Polycystic Kidney Disease(PKD) is a kind of genetic kidney disease characterized with multiple fluid-filled cysts in the kidneys. When you grow old, the cysts can also enlarge with you and oppress the neighboring renal tissues or organs. At present, it has been a leading cause of Kidney Failure.

    Types

    In clinical, there are two types of PKD: autosomal dominant polycystic kidney disease(ADPKD) and autosomal recessive polycystic kidney disease(ARPKD). The former is very common in patients between 30 to 40 years old. If either of the parents have this disease, the prevalence of each of their children can be 50%. However, the latter is more likely to occur in infants and the onset rate of the children is 25% if both of their parents are PKD patients.

    Causes

    In most cases, PKD happens in patients with a family history. And the main causes of this disease include:

    1) Congenital dysontogenesis or genic mutation.

    2) Toxins: Toxins can damage all kinds of cells, tissues and organs. Also it is one of the main reasons causing congenital dysontogenesis and genic mutation.

    3) Infections: Infections can make the internal environment changes and create a good environment for cystic genes to change. In that case, the activity of inner factor of cysts will be increased, so the growth of cysts will speed up. The common infections include: urinary tract infection, gastrointestinal tract infection, skin infection, upper respiratory tract infection, trauma infection and so on.

    4) Diet and lifestyle: Unreasonable eating habit may cause many diseases occur. Dink alcohol and smoking can speed up gene expression and the growth of cysts.

    5) Too much psychological pressure or bad mood: Bad mood can decrease people's immunity. As a result, many toxins and virus will be likely to attack and affect internal environment.

    The above is introduction of basic knowledge about Polycystic Kidney Disease. If you want to know more, please feel free to consult our online doctor.


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