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    Home > Related Disease > Polycystic Kidney Disease > Polycystic Kidney Disease Basics >

    What Is Polycystic Kidney Disease (PKD)

    2013-10-30 14:00| Font Size A A A

    Polycystic Kidney Disease, PKD Polycystic Kidney Disease (PKD) is commonly seen genetic CKD with cysts of varying dimensions on bilateral kidneys, which progressively increases and damages renal structures and functions, thus further causing End Stage Renal Failure.

    According to distinct mode of inheritance, Polycystic Kidney Disease is divided into autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). Patients with the former disease is usually detected in youth to middle age while the latter can be diagnosed in babyhood.

    While ADPKD is known as adult Polycystic Kidney Disease with morbidity of 1/1000~1/4000, which is most common genetic kidney disease of single gene for patients in their 30’s to 50’s. As a matter of fact, this is not an exact appellation that ADPKD can attack people in all ages. Moreover, ADPKD is a kind of systemic damage rather than kidney related only, which includes hepatic cysts, pancreatic cysts, intracranial aneurysm and heart valve disorders, etc. It is already confirmed that PKD1HE and PKD2 are two kinds of mutant genes of Polycystic Kidney Disease. It is worth noting that there are 50% of patients more than 60 will develop into End Stage Renal Failure, which accounts for 5%~10% of diseased causes.

    ARPKD is recessive genetic CKD with significant attack in babyhood, which is used to be called infantile Polycystic Kidney Disease while few cases are children or teenagers. 1/10000~1/40000 of patients contract ARPKD, which is accompanied with involved livers such as hepatic cysts. PKHD1 is discovered as virulence gene that 50% of diseased children die for respiratory failure or Renal Failure in few days even few hours while survived adults mainly behave as spindle expansion of renal collecting duct, which further leads to Renal Failure with intrahepatic duct dilatation, congenital hepatic fibrosis and portal hypertension, etc.

    What is Polycystic Kidney Disease? As a matter of fact, it is promising for patients to be reversed fundamentally in most cases as long as they receive earlier detection and treatment. If you want to know more about natural treatments which are optimal therapies to remedy CKD timely and effectively, please leave a message below or talk to our online service for free.

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