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    Home > Related Disease > Lupus Nephritis > Lupus Nephritis Basics >

    What Is Stage 4 Lupus Nephritis

    2014-05-12 03:42| Font Size A A A

    What Is Stage 4 Lupus NephritisLupus Nephritis is caused by systemic lupus erythematosus, which is an autoimmune disease that can cause damage in many body systems. Lupus nephritis is divided into five stages, and stage 4 is advanced stage.

    What is stage 4 lupus nephritis?

    Chronic kidney disease is divided into five stages according to GFR, and the GFR range of stage 4 CKD is 15~30ml/min. Healthy people’s GFR can reach 120ml/min, so the GFR range of stage 4 lupus nephritis is very low.

    In fact, there are about one million nephrons in our kidney, and patient’s kidney disease will damage these nephrons. As a result, the filtered fluid will reduce, which will cause patients to have low GFR. Stage 4 lupus nephritis means a large amount of nephrons are damaged.

    What will happen if patients have stage 4 lupus nephritis?

    Kidney is an important organ of our body, which is in charge of the metabolic balances of electrolytes, fluid and acid-base. If patient has stage 4 lupus nephritis, that means patient’s kidney function is damaged severely, and patients will have the metabolic disorders of electrolytes, fluid and acid-base, which can cause many complications. For example, patients with stage 4 lupus nephritis can have complications like cardiovascular disease, renal osteopathy, anemia, gout, nerve problems, etc.

    When patients have severe complications caused by their low kidney function and severely metabolic disorders, patients will need dialysis to correct the metabolic imbalances and remove the metabolic wastes. In fact, most patients will be recommended to accept dialysis when they have 15% remaining kidney function, and it means patients are in later stage of stage 4 CKD. For patients with stage 4 lupus nephritis, they may begin to accept dialysis. Thereby, when lupus nephritis progresses into stage 4, patient’s condition is very severe.

    Kidney disease can cause many complicated problems, and patients should do tehir best to improve their condition. If you need any help, you can leave us a message about your details. We will provide the guidance you need or do what we can to help you.


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