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    Home > Related Disease > IgA Nephropathy > IgA Nephropathy Treatment >

    IgA Nephropathy Patients Should Avoid Steroids In These Conditions

    2017-07-10 03:50| Font Size A A A

    Avoid Steroids In IgA Nephropathy Steroid is always regarded as the first medicine for chronic kidney disease. Among kidney patients, roughly half of patients suffer from IgA Nephropathy. Generally, doctors all agree that if 24h urine protein quantity is 1g, glucocorticoid is used.

    Doubt for steroids

    As we all know, steroids have lots of side effects. Is it worth to take steroids? Patients are at sea and doctors are entangled.

    Ni 2011, there was a research that from 70 hospitals, 500 IgA Nephropathy patients are chosen and are given steroids. These patients are divided into two groups. One group is given methyprednisolone and the other group is given hypotensive medicines.

    The failure of steroids

    2 years later, 20 patients suffer from severe complications including death. It is 5 times than patients without steroids.

    Although steroids can reduce proteinuria to some extent in IgA Nephropathy, they will increase the risk of infection. Even some patients experience fatal infection.

    Can you take steroids?

    Half of IgA Nephropathy is glomerulonephritis but some are still not. Then how do patients know if they are IgA Nephropathy or not? Do they need to take steroids?

    Look at the following indexes:

    1. Occult blood or gross hematuria

    2. Serum IgA is larger than 3.15g/L

    3. The specific value of IgA/C3 is larger than 3

    4. Urinary erythrocyte deformation rate is larger than 80% and Acanthoid erythrocytes is larger than 5%.

    5. The specific value of Serum CD4/CD8 is higher

    If you have the above indexes, you are suffering from IgA Nephropathy. When your urine protein is 1g, you can reject steroids when your doctor prescribe steroids to you.

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