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    Home > Evaluate with CKD > Lab Test > GFR >

    If An Increase in Creatinine Level Results in A Lower GFR

    2014-04-23 01:32| Font Size A A A

    If An Increase in Creatinine Level Results in A Lower GFRCreatinine is a dangerous condition, because it often indicates patients have severe kidney damage. As a result, patient’s kidney function will be damaged by his kidney disease, and that can cause patients to have low kidney function, which will lead to a low GFR. Well then, if an increase in creatinine level results in a low GFR?

    To know the answer of this question, we should know the causes of high creatinine and low GFR, and it is necessary for patients to have a better understanding about the relation between high creatinine and low GFR.

    Why does creatinine level increase?

    Creatinine is a metabolic waste of muscle, and it should be filtrated out by kidney. Because creatinine will not be reabsorbed back to blood by kidney tubule, so its level in blood can reflect patient’s kidney function.

    On the other hand, kidney has strong metabolic ability, and it is not easy for patients to have high creatinine because high normal kidney function will be able to guarantee our body health. Thereby, if patient with kidney disease finds he has high creatinine, it means at least half normal kidney function is damaged.

    Can increased creatinine level result in lower GFR?

    GFR refers to how much blood has been filtered by kidney in unit time, and there are about one million nephrons in each kidney, which is in charge of its filtering function. Kidney disease can damage patient’s nephrons, which will lower patient’s GFR.

    Thereby, both high creatinine and low GFR are caused by patient’s low kidney function, and they can not aggravate patient’s kidney damage. Thereby, there is no causal relationship between them, and high creatinine can not cause patients to have lower GFR.

    Kidney disease can cause many health problems in our body, and patients should do their best to improve their condition. If you have any trouble in dealing with your condition, you can contact our online experts. We will provide the guidance you need or do what we can to help you.


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